Natural Killer Cells
Use
Low numbers of natural killer (NK) cells are found in individuals who are susceptible to viral infections such as cytomegalovirus and varicella, highlighting the test’s role in assessing immune competence and surveillance against viral and malignant cells. Quest Diagnostics Nichols Institute performs this assay to measure NK cell levels including absolute lymphocytes, absolute NK cell counts, and percent NK cells as CD3–CD16+CD56+. Clinical interpretation supports evaluation of immune dysfunction or immune status monitoring.
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
Cell-based / Cytometry (Flow Cytometry)
Biomarkers
Absolute Lymphocytes
AnalyteCD3‑/CD16+CD56+ (%)
AnalyteNK Cells CD3-CD16+CD56+ (Abs)
Analyte
Result Turnaround Time
2-3 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL
Minimum Volume
0.5 mL
Container
EDTA (lavender-top) tube
Collection Instructions
Do not freeze. Submit EDTA tube at room temperature.
Causes for Rejection
Hemolysis; Received refrigerated; Received frozen
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | Unacceptable |
| Frozen | Unacceptable |
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