Natural Killer Cell and Activated T-Cell Profile/IL-2r
Also known as: CD25, Interleukin-2 Receptor, TAC Antigen
Use
Assess changes in T-lymphocyte surface markers that may indicate immune stimulation
Special Instructions
Not provided.
Limitations
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration. The results should be used in conjunction with clinical findings and other diagnostic tests. Hemolysis, clotted specimens, or specimens that have been refrigerated or frozen are causes for rejection and can affect the accuracy of test results.
Methodology
Cell-based / Cytometry (Flow Cytometry)
Biomarkers
Activated T Cells (CD3+CD25+)
Cell TypeNatural Killer Cells (CD3-CD56+)
Cell TypeT Cells (CD3+)
Cell Type
LOINC Codes
- 742-7 - Monocytes # Bld Auto
- 711-2 - Eosinophil # Bld Auto
- 704-7 - Basophils # Bld Auto
- 71695-1 - Imm Granulocytes NFr Bld Auto
- 53115-2 - Imm Granulocytes # Bld Auto
- 58413-6 - nRBC Bld Auto-Rto
- 18314-5 - Morphology Bld-Imp
- 42188-3 - CD3+CD16+CD56+ Cells # Bld
- 42189-1 - CD3+CD16+CD56+ Cells NFr Bld
- 8122-4 - CD3 Cells # Bld
- 8124-0 - CD3 Cells NFr Bld
- 26997-7 - CD3+CD25+ Cells # Bld
- 13333-0 - CD3+CD25+ Cells NFr Bld
- 6690-2 - WBC # Bld Auto
- 789-8 - RBC # Bld Auto
- 718-7 - Hgb Bld-mCnc
- 4544-3 - Hct VFr Bld Auto
- 787-2 - MCV RBC Auto
- 785-6 - MCH RBC Qn Auto
- 786-4 - MCHC RBC Auto-EntMCnc
- 788-0 - Erythrocyte DistWidth Bld Auto
- 777-3 - Platelet # Bld Auto
- 770-8 - Neutrophils NFr Bld Auto
- 736-9 - Lymphocytes NFr Bld Auto
- 5905-5 - Monocytes NFr Bld Auto
- 713-8 - Eosinophil NFr Bld Auto
- 706-2 - Basophils NFr Bld Auto
- 75652-8 - Imm Lymphs Bld Ql
- 751-8 - Neutrophils # Bld Auto
- 731-0 - Lymphocytes # Bld Auto
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
Fill tube(s) to capacity.
Minimum Volume
Not provided
Container
Lavender-top (EDTA) tube and yellow-top (ACD-A) or (ACD-B) tube
Collection Instructions
Invert tube 8 to 10 times immediately after collection. To preserve cellular viability, collect specimen so it will arrive in the laboratory within 48 hours of collection. Indicate date and time of venipuncture on the tube(s) and on the test request form.
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Hemolysis; specimen refrigerated or frozen; clotted specimen; contaminated specimen
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Yellow-top (ACD-A) or (ACD-B) tube: 2 days; Lavender-top (EDTA) tube: 1 day |
| Refrigerated | Unstable |
| Frozen | Unstable |
Other tests from different labs that may be relevant