Helper/Suppressor and Natural Killer Cell Profile
Use
Monitor patients helper/suppressor T-cell status; assess other changes in T-cell surface markers that may indicate changes in immune status
Special Instructions
Not provided.
Limitations
The test must be conducted within the specified stability periods to ensure accurate results. Room temperature stability for yellow-top (ACD-A) or (ACD-B) tube is 2 days, while for lavender-top (EDTA) tube it is 1 day. The specimen is unstable if refrigerated or frozen. Factors such as hemolysis, clotting, or contamination can cause sample rejection. Additionally, proper collection and handling are crucial to maintain specimen integrity.
Methodology
Cell-based / Cytometry (Flow Cytometry)
Biomarkers
LOINC Codes
- 53759-7 - Natural killer cell Pnl Bld FC
- 8112-5 - CD3-CD16+CD56+ Cells NFr Bld
- 9728-7 - CD3-CD16+CD56+ Cells # Bld
- 8122-4 - CD3 Cells # Bld
- 24467-3 - CD3+CD4+ Cells # Bld
- 14135-8 - CD3+CD8+ Cells # Bld
- 8124-0 - CD3 Cells NFr Bld
- 8123-2 - CD3+CD4+ Cells NFr Bld
- 8101-8 - CD3+CD8+ Cells NFr Bld
- 54218-3 - CD3+CD4+ Cells/CD3+CD8+ Cll Bld
- 6690-2 - WBC # Bld Auto
- 789-8 - RBC # Bld Auto
- 718-7 - Hgb Bld-mCnc
- 4544-3 - Hct VFr Bld Auto
- 787-2 - MCV RBC Auto
- 785-6 - MCH RBC Qn Auto
- 786-4 - MCHC RBC Auto-EntMCnc
- 788-0 - Erythrocyte DistWidth Bld Auto
- 777-3 - Platelet # Bld Auto
- 770-8 - Neutrophils NFr Bld Auto
- 736-9 - Lymphocytes NFr Bld Auto
- 5905-5 - Monocytes NFr Bld Auto
- 713-8 - Eosinophil NFr Bld Auto
- 706-2 - Basophils NFr Bld Auto
- 75652-8 - Imm Lymphs Bld Ql
- 751-8 - Neutrophils # Bld Auto
- 731-0 - Lymphocytes # Bld Auto
- 742-7 - Monocytes # Bld Auto
- 711-2 - Eosinophil # Bld Auto
- 704-7 - Basophils # Bld Auto
- 71695-1 - Imm Granulocytes NFr Bld Auto
- 53115-2 - Imm Granulocytes # Bld Auto
- 58413-6 - nRBC Bld Auto-Rto
- 18314-5 - Morphology Bld-Imp
- 35332-6 - Neuts Band NFr Bld Auto
- 28541-1 - Metamyelocytes NFr Bld
- 26498-6 - Myelocytes NFr Bld
- 19252-6 - Megakaryocytes NFr Bld
- 55433-7 - Immature cells NFr Bld
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
Fill tube(s) to capacity.
Minimum Volume
Not provided
Container
Lavender-top (EDTA) tube and yellow-top (ACD-A or ACD-B) tube
Collection Instructions
Invert tube 8 to 10 times immediately after collection. Indicate date and time of venipuncture on the tube(s) and on the test request form.
Storage Instructions
Maintain specimen at room temperature. Do not freeze or refrigerate.
Causes for Rejection
Hemolysis; specimen refrigerated or frozen; clotted specimen; contaminated specimen
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Yellow-top (ACD-A or ACD-B) tube: 2 days; Lavender-top (EDTA) tube: 1 day |
| Refrigerated | Unstable |
| Frozen | Unstable |
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