Liver Fibrosis Risk Profile With Hepatic Function Panel, Complete Blood Count (CBC) With Differential, FIB-4, and APRI
Also known as: Fatty Liver Disease, Liver Fibrosis, NAFLD, NASH, Nonalcoholic Fatty Liver Disease
Use
Screening patients suspected to be at risk for liver fibrosis.
Special Instructions
The test includes a comprehensive analysis of hematocrit, hemoglobin, RBC, WBC, liver enzymes like ALT/AST, albumin, bilirubin, and other components in the CBC and hepatic function panel. Patients should ensure proper specimen collection, adhering to collection instructions for optimal results.
Limitations
Results may be affected by clumping, which can cause false low platelet counts, and platelet satellitism, which causes pseudothrombocytopenia. RBC or WBC fragments, including leukemic cells and neutrophil pseudoplatelets, may cause falsely elevated counts. Specific findings in the staining smeared assessment may indicate further investigation is required, according to numeric or instrument flagging criteria.
Methodology
Other
Biomarkers
LOINC Codes
- 98491-4
- 2885-2
- 1751-7
- 1975-2
- 1968-7
- 6768-6
- 1920-8
- 1742-6
- 86465-2
- 98488-0
- 6690-2
- 789-8
- 718-7
- 4544-3
- 787-2
- 785-6
- 786-4
- 788-0
- 777-3
- 770-8
- 736-9
- 5905-5
- 713-8
- 706-2
- 75652-8
- 751-8
- 731-0
- 742-7
- 711-2
- 704-7
- 71695-1
- 53115-2
- 58413-6
- 18314-5
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
4 mL
Minimum Volume
2.5 mL
Container
Gel-barrier tube or red-top tube
Collection Instructions
Separate serum from cells within 45 minutes of collection. Invert EDTA tube immediately 8 to 10 times once tube is filled.
Storage Instructions
Room temperature
Causes for Rejection
Gross hemolysis; improper labeling
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Serum: Direct Bilirubin - 2 days; All others - 3 days; Whole blood: 1 day |
| Refrigerated | Serum: Bilirubin and Direct Bilirubin - 3 days; All others - 14 days; Whole blood: 3 days |
| Frozen | Serum: SGPT(ALT) - Unstable; All others - 14 days; Whole blood: Unstable |