Macroprolactin
Use
The Macroprolactin test is used to measure various forms of prolactin in the blood, specifically focusing on the determination of macroprolactin levels. Macroprolactin, a complex form of prolactin, can affect the diagnosis of hyperprolactinemia and needs to be differentiated from monomeric prolactin, which is the bioactive form responsible for clinical symptoms. This test is crucial for patients suspected of high prolactin levels to assure accurate diagnosis and treatment.
Special Instructions
For accurate results, ensure the patient has been awake for at least two hours before sample collection. Carefully process the specimen by separating serum or plasma from cells within 45 minutes of collection and transferring it to a plastic transport tube before freezing.
Limitations
This test has not been cleared or approved by the FDA, which might limit its acceptance in certain clinical settings. The result turnaround time can vary if additional confirmatory or reflex tests are required, potentially extending beyond the usual 5 to 10 days.
Methodology
Immunoassay (ECLIA)
Biomarkers
LOINC Codes
- 38926-2
- 2842-3
- 42607-2
- 51441-4
Result Turnaround Time
5-10 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL
Container
Gel-barrier tube, red-top tube, serum transfer tube
Collection Instructions
Do not draw sample until patient has been awake for at least two hours. Separate serum or plasma from cells within 45 minutes of collection. Transfer specimen to plastic transport tube before freezing.
Storage Instructions
Freeze.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 6 months |