Markers of Coagulation Activation (Esoterix)
Use
The Markers of Coagulation Activation (Esoterix) test is used to measure factors associated with coagulation activation. It includes D-dimer quantification, which serves as an aid in diagnosing venous thrombosis, alongside measurements of prothrombin fragment 1+2 and thrombin antithrombin complex. High levels of these markers can indicate coagulation activation, aiding in the assessment of thrombotic disorders.
Special Instructions
Not provided.
Limitations
The D-dimer quantitative assay is not FDA approved for the exclusion of venous thrombosis. Moreover, pre-analytical conditions such as a difficult draw may spuriously increase test results, affecting the reliability of the measurements for prothrombin fragment 1+2 and thrombin antithrombin complex.
Methodology
Immunoassay (ELISA)
Biomarkers
D-Dimer Quantitative
AnalyteProthrombin Fragment 1+2 MoAb
AnalyteThrombin Antithrombin Complex
Analyte
LOINC Codes
- 14182-0 - TAT Ag PPP IA-mCnc
- 25742-8 - Pro Frg1+2 SerPl-sCnc
- 48065-7 - D Dimer PPP FEU-mCnc
- 48065-7 - D Dimer PPP FEU-mCnc
- 25742-8 - Pro Frg1+2 SerPl-sCnc
- 14182-0 - TAT Ag PPP IA-mCnc
Result Turnaround Time
3-9 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
2 mL
Minimum Volume
2 mL
Container
Blue-top (sodium citrate) tube
Collection Instructions
Plasma must be separated from cells within 45 minutes of venipuncture. Send plasma in a plastic transport tube.
Storage Instructions
Freeze
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