NMR LipoProfile® With Insulin Resistance Markers Without Lipids (Without Graph)

Clinical Use

Use

NMR LDL-P is a management tool used in appropriate risk-risk patients (type 2 diabetes mellitus, metabolic syndrome, CVD risk equivalent, statin-treated patients) to adjudicate response to treatment and guide adjustment in therapy. It is used in conjunction with other lipid measurements and clinical evaluation to aid in the management of lipoprotein disorders associated with cardiovascular disease.

Special Instructions

Not provided.

Limitations

This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the FDA. Results may be less accurate if the patient is non-fasting as the LP-IR score is affected by such conditions. The test may not accurately reflect insulin resistance and diabetes risk if certain parameters associated with the LP-IR score are not followed.

Test Details

Methodology

Other

Biomarkers

9 targets

HDL SizeHDL-P (Total)Large HDL-PLarge VLDL-PLDL SizeLDL-PLP-IR ScoreSmall LDL-P+1 more

LOINC Codes

Order Codes

884209

Result Codes

54434-6 - LDL SerPl-sCnc
49748-7 - HDL SerPl-sCnc
43727-7 - LDL Small SerPl-sCnc
17782-4 - LDL SerPl Qn
43728-5 - VLDL large SerPl-sCnc
43729-3 - HLD.large SerPl-sCnc
62254-8 - VLDL SerPl Qn
62253-0 - HDL SerPl Qn
62255-5 - LP-IR score SerPl

Result Turnaround Time

2-3 days

Specimen

Serum

Volume

2 mL

Minimum Volume

1 mL

Container

NMR LipoTube (black-and-yellow-top tube), plain red-top tube, lavender-top (EDTA-no gel) tube, or green-top (heparin-no gel) tube

Collection Instructions

Collect specimen in NMR LipoTube (black-and-yellow-top tube), which is the preferred container. Plain red-top, green-top (heparin-no gel) or lavender-top (EDTA-no gel) tubes also are acceptable. Serum or plasma drawn in gel-barrier collection tubes other than the NMR LipoTube should not be used. Gently invert tube eight to 10 times to mix contents and allow specimen to clot for 30 minutes upright at room temperature prior to centrifugation. Centrifuge specimen within two hours of collection at 1600 to 1800 xg for 10 to 15 minutes to separate serum/plasma from the red cells and avoid red cell contamination during shipment.

Patient Preparation

Patient should be fasting for eight hours.

Storage Instructions

Refrigerate all acceptable tube types as soon as possible after centrifugation and within 24 hours of collection. Keep refrigerated prior to shipment, and ship on frozen cool packs. Do not store at room temperature. Do not freeze the sample.

Causes for Rejection

Unspun specimens; plasma/serum contaminated with red cells; citrated plasma (light blue-top tube); gross hemolysis; specimen received in inappropriate container; specimen stored at room temperature for more than a total preanalytical time of 24 hours; specimen more than six days old.