Red Blood Cell (RBC) Antigen Typing: A1
Use
Group A subgroup typing of a potential organ donor for A1 may be important, as it may preclude a solid organ transplant to a group O or group B recipient. ABO antigens are expressed on the vascular endothelium of organs. Major incompatibility between donor ABO antigens and recipient plasma can result in acute humoral rejection of the transplanted organ. The occurrence of the A1 antigen is 34% in Caucasians, 19% in Blacks, and 27% in Asians. A1 is present in 80% of group A individuals.
Special Instructions
Not provided.
Limitations
The presence of potent cold agglutinins, a positive direct antiglobulin test, and some cases of bacteremia may interfere with test interpretation.
Methodology
Other
Biomarkers
A1 Antigen
Protein
LOINC Codes
- 844-1 - A1 Ag RBC Ql
- 844-1 - A1 Ag RBC Ql
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
1 mL
Minimum Volume
0.5 mL
Container
Lavender-top (EDTA) tube
Storage Instructions
Specimens should be tested as soon as possible or within 72 hours of collection. Samples that cannot be tested immediately should be stored at 2°C to 8°C. Do not freeze red cells.
Causes for Rejection
Gross hemolysis; bacterial or other contamination
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 72 hours |
Other tests from different labs that may be relevant