Casandra
Casandra Test Code LC78380Version 1 (DRAFT)
Performing Lab
Sjögren's Antibodies (Anti-SS-A/Anti-SS-B)
Also known as: Anti-La, Anti-Ro
Clinical Use
Order TestUse
Aids in the diagnosis of Sjögren's syndrome (especially with vasculitis) and lupus patients with Sjögren's overlap syndrome.
Special Instructions
Not provided.
Limitations
The test may have limitations in detecting SS-A by immunofluorescence techniques due to solubility issues. Also, there may be variability in the presence of antibodies with certain conditions like nephritis in ANA-positive individuals.
Test Details
Methodology
Cell-based / Cytometry (Flow Cytometry)
Biomarkers
Anti-SS-A
ProteinIgG class antibodies
Expression • Ordinal Score (e.g., TPS, CPS, H-score)
Anti-SS-B
ProteinIgG class antibodies
Expression • Ordinal Score (e.g., TPS, CPS, H-score)
LOINC Codes
Order Codes
- 103139-2 - SL Panel SerPl
Result Codes
- 17792-3 - ENA SS-A Ab Ser-aCnc
- 17791-5 - ENA SS-B Ab Ser-aCnc
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Red-top tube or gel-barrier tube
Storage Instructions
Room temperature
Causes for Rejection
Hemolysis; icterus; lipemia; bacterial contamination
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
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