Cryptococcus Antibody
Use
This test is intended to detect antibodies against Cryptococcus species (principally C. neoformans and C. gattii) and may indicate current or past infection. It is of limited diagnostic utility, particularly in immunocompromised individuals, as antibody responses may be absent or unreliable. As such, antigen testing (e.g., cryptococcal antigen) is preferred for active infection.
Special Instructions
Reference Test Name: Cryptococcus Antibody. Reference Lab Test Code: 30429. Send out Monday through Friday with the Quest courier.
Limitations
Antibody testing for Cryptococcus has low sensitivity and may yield false negatives in immunocompromised patients; cross‑reactivity with other fungi can reduce specificity. Titers may persist after infection and do not reliably indicate active disease.
Methodology
Other
Biomarkers
Result Turnaround Time
3-6 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
Preferred Vol: 2.0 mL
Minimum Volume
Minimum Vol: 1.0 mL
Container
Gold SST, Gold Microtainer, or Red
Storage Instructions
Separate from cells within two hours; transfer serum to plastic aliquot tube
Causes for Rejection
Gross hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 d |
| Refrigerated | 14 d |
| Frozen | 30 d |