Cyclosporine A Peak (2 Hour), Blood
Use
Cyclosporine A (cyclosporin A) is an immunosuppressant therapeutic agent used in the prevention of organ graft rejection. Clinical measurement of blood levels is required due to inter-individual variability in metabolism as well as toxicity associated with excessive dosage.
Special Instructions
Not provided.
Limitations
No definitive therapeutic or toxic ranges have been established. Optimal blood drug levels are influenced by type of transplant, patient response, time post‑transplant, co‑administration of other drugs, and drug formulation. The following peak ranges are suggested guidelines: de novo 1500–1700 mcg/L; 1 Year 300–600 mcg/L.
Methodology
Immunoassay (Immunoassay)
Biomarkers
Result Turnaround Time
3-4 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
2 mL preferred
Minimum Volume
1 mL minimum
Container
EDTA (lavender‑top) tube
Collection Instructions
Collect as a peak, 2 hours post‑dose
Causes for Rejection
Clotted specimen
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 7 days |
| Frozen | 30 days |