Oxycodone and Metabolite, Quantitative, Serum
Also known as: Percocet®
Use
For therapeutic drug monitoring of oxycodone (Oxycontin®, Percocet®, Percodan®). Oxycodone is a semisynthetic opioid analgesic. Steady‑state concentration is reached in 24–36 hours after initiation of therapy. Elimination half‑life of oxycodone is approximately 4.5 hours for controlled‑release and 3.2 hours for immediate‑release formulations. Oxymorphone is a minor but active metabolite present at lower concentrations. Therapeutic concentrations for oxymorphone have not been established.
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
Mass Spectrometry
Biomarkers
Oxycodone
AnalyteOxymorphone
Analyte
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
5 mL
Minimum Volume
3 mL
Container
red‑top tube (no gel)
Collection Instructions
Do not use serum separator tubes
Causes for Rejection
Use of serum separator tube (SST)
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 7 days |
| Frozen | 7 days |
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