Thyroglobulin Panel
Also known as: ATG and TG, TG and ATG
Use
Thyroglobulin (TG) is a secretory product only of the thyroid gland. The major clinical use of serum TG measurement is to monitor—but not to diagnose—patients with well‑differentiated thyroid cancers. Measurement of thyroglobulin after thyroidectomy and ablation of the thyroid gland is useful to determine metastases. Deficient TG synthesis is observed in infants with goitrous hypothyroidism. Most patients with thyroid autoimmune disease have thyroglobulin antibody. In immunometric (sandwich) assays, TG antibody interference typically produces inappropriately low TG results, most likely caused by endogenous TG immune complexes that block one or more of the reagent antibodies from binding endogenous TG.
Special Instructions
Patient Preparation: Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega‑doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Limitations
Not provided.
Methodology
Immunoassay (Multiplex Protein Panel)
Biomarkers
LOINC Codes
- 8098-6
- 8098-6
- 3013-0
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL
Patient Preparation
See specialNotes
Causes for Rejection
Gross hemolysis; grossly lipemic
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 7 days |
| Frozen | 28 days |