17-Hydroxypregnenolone 60-Minute Timed Specimen
Also known as: OHPRGN 60
Use
The 17-Hydroxypregnenolone 60-Minute Timed Specimen test measures the level of 17-Hydroxypregnenolone in the serum or plasma after a specific duration, aiding in the evaluation of adrenal function and the diagnosis of conditions related to steroid synthesis abnormalities. This test is crucial for assessing disorders like congenital adrenal hyperplasia and for monitoring the effectiveness of treatment in these conditions.
Special Instructions
For accurate results, it is essential to maintain the specimen frozen during storage and transport. Ensure that serum or plasma is separated from cells as soon as possible or within two hours of collection to avoid degradation.
Limitations
The test may be affected by improper handling and storage, such as failing to freeze the specimen immediately, which can lead to degradation of the analyte. Another limitation includes potential interference from other steroids or similar compounds in the blood, affecting the specificity of the test results. Additionally, results must be interpreted in the context of the patient's clinical presentation and other diagnostic findings.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 49325-4
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.25 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Collect specimen in a serum separator tube. Alternative acceptable tubes include plain red, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin). Separate serum or plasma from cells ASAP or within 2 hours of collection.
Storage Instructions
Freeze immediately after transfer to the ARUP Standard Transport Tube.
Causes for Rejection
Refrigerated or room temperature specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | Unacceptable |
| Frozen | 6 months |