25-Hydroxyvitamin D2 and D3 by Tandem Mass Spectrometry, Serum and Plasma
Also known as: VITD2D3TMS
Use
This test measures the levels of 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3 in the serum or plasma, which are essential for understanding the vitamin D status of a patient. It is particularly useful for assessing individuals with vitamin D insufficiency or deficiency who do not respond to supplementation. It is not the preferred test for initial evaluation of vitamin D insufficiency; a different test is recommended for that purpose. The test provides separate values for both Vitamin D2 and D3, in addition to the total concentration.
Special Instructions
Not provided.
Limitations
This test has specific limitations, such as the inability to provide reliable results for infant specimens less than one year of age, hence they are referred to another laboratory. The test is developed and characterized by ARUP Laboratories and has not been cleared or approved by the US Food and Drug Administration. Potential users should note that it is intended for clinical purposes and performed in a CLIA certified laboratory.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
25-Hydroxyvitamin D2
Analyte25-Hydroxyvitamin D3
Analyte
LOINC Codes
- 62292-8 - 25(OH)D3+25(OH)D2 SerPl-mCnc
- 62292-8 - 25(OH)D3+25(OH)D2 SerPl-mCnc
- 1989-3 - 25(OH)D3 SerPl-mCnc
- 49054-0 - 25(OH)D2 SerPl-mCnc
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.15 mL
Container
Plain red or serum separator tube. Also acceptable: Green (sodium heparin), lavender (EDTA), or pink (K2EDTA).
Storage Instructions
Refrigerated.
Causes for Rejection
Room temperature specimens older than 24 hours.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 1 week |
| Frozen | 6 months |
Other tests from different labs that may be relevant