Arsenic, Fractionated, Urine
Also known as: AS UF
Use
This test is useful when exposure to arsenic is known but the species is uncertain. It is used to distinguish between organic, inorganic, and methylated species of arsenic in urine. The inorganic species of arsenic are most toxic, whereas the organic species are considered nontoxic and typically arise from dietary sources. Methylated species arise primarily from metabolism of inorganic species but may also come from dietary sources and are of moderate toxic potential. This test provides insight into arsenic exposure and assists in evaluating overall toxicity risk associated with different arsenic species.
Special Instructions
For initial testing, Arsenic, Urine with Reflex to Fractionated (0025000) is preferred if exposure to arsenic is suspected and species differentiation is needed. Specimens must be collected in a plastic container and should be refrigerated during collection. It is crucial to note the total volume and collection time interval on the transport tube and request form to ensure accurate testing.
Limitations
Elevated results may arise from contamination due to the use of non-trace element-free collection containers or from urine collected within 48 hours after administration of gadolinium-containing contrast media. Specimen contamination with blood or fecal matter also invalidates the sample. If contamination is suspected, a second specimen collected in a certified trace element-free container is advisable for confirmation. The test may yield levels lower than the total arsenic concentration if unidentified organic species of arsenic are present.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 12481-8
- 53779-5
- 53778-7
- 93479-4
Result Turnaround Time
1-10 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
8 mL
Minimum Volume
2 mL
Container
ARUP Trace Element-Free Transport Tubes
Collection Instructions
Collect in a plastic container. Refrigerate during collection. Record total volume and time interval on transport tube and test request form.
Storage Instructions
Refrigerated. Also acceptable: Room temperature or frozen.
Causes for Rejection
Urine collected within 48 hours after administration of gadolinium (Gd) contrast media, acid preserved urine, specimens contaminated with blood or fecal material, non-trace element-free transport tubes except the original device.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 2 weeks |
| Refrigerated | 2 weeks |
| Frozen | 2 months |