Arsenic, Urine with Reflex to Fractionated

Also known as: ARS U

Clinical Use

Use

This test is used for the assessment of acute or chronic arsenic exposure. It differentiates between toxic inorganic and methylated species as well as benign organic forms. Results are reported as total inorganic, total methylated, and organic arsenic. The test includes reflex fractionation to determine different arsenic species if total arsenic levels are elevated, which aids in understanding the exposure type.

Special Instructions

Not provided.

Limitations

Elevated arsenic results may arise from contamination during collection using non-trace element-free containers. Elevated results should be confirmed with a second specimen collected in a trace element-free container. Kidneys in patients with impaired function can influence test results if contrast media was administered up to 14 days before collection.

Test Details

New York Approved

Methodology

Mass Spectrometry

Biomarkers

2 components

Arsenic QuantificationArsenic Fractionation

LOINC Codes

Result Codes

35674-1 - Creat ?Tm Ur-mCnc
2162-6 - Creat 24h Ur-mRate
30924-5 - Arsenic ?Tm Ur-mCnc
5587-1 - Arsenic 24h Ur-mRate
13463-5 - Arsenic/Creat Ur
19153-6 - Specimen vol ?Tm Ur
30211-7 - Specimen collect Time Spec

Result Turnaround Time

1-5 days

Specimen

Urine

Volume

24-hour or random collection

Minimum Volume

2 mL

Container

Plastic container and refrigerated during collection

Collection Instructions

Transfer an 8 mL aliquot from a well-mixed collection to ARUP Trace Element-Free Transport Tubes.

Patient Preparation

Avoid nutritional supplements, vitamins, minerals, nonessential over-the-counter medications, and seafood for 48-72 hours. Avoid collection within 72 hours of contrast media exposure.