B Cell Specific Octamer Binding Protein-1 (BOB-1) by Immunohistochemistry
Also known as: BOB1 IHC
Use
This test is used for staining tissue samples to identify the presence of B Cell Specific Octamer Binding Protein-1 (BOB-1). It assists in the diagnosis and classification of certain B cell lymphomas by highlighting B cells within tissue sections using the immunohistochemistry method. The presence of BOB-1 can be an important factor in determining the nature of lymphoproliferative disorders.
Special Instructions
IMMUNOHISTOCHEMISTRY ORDERING AND SUBMISSION DETAILS: Submit electronic request. If you do not have electronic ordering capability, use an ARUP Immunohistochemistry Stain Form (#32978) with an ARUP client number. For additional technical details, contact ARUP Client Services at (800) 522-2787.
Limitations
This test has not been cleared or approved by the FDA and is considered a laboratory-developed test (LDT). The assay is intended for use in a clinical laboratory setting and the interpretation of results should be made within the context of the larger clinical picture. The staining and interpretation require professional expertise and the test is performed as a stain and return (technical) service only, meaning no clinical interpretation is provided as part of the service.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 53637-5
- 94736-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
2 slides
Container
Paraffin block or 5 unstained positively charged slides
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen (cells must be prepared into a cellblock). Protect paraffin block and/or slides from excessive heat. Transport tissue block or 5 unstained (3- to 5-micron thick sections), positively charged slides in a tissue transport kit (ARUP supply #47808).
Storage Instructions
Room temperature or refrigerated. Ship in cooled container during summer months.
Causes for Rejection
Specimens submitted with non-representative tissue type. Depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |