B Cell Specific Octamer Binding Protein-1 (BOB-1) by Immunohistochemistry

Also known as: BOB1 IHC

Clinical Use

Use

This test is used for staining tissue samples to identify the presence of B Cell Specific Octamer Binding Protein-1 (BOB-1). It assists in the diagnosis and classification of certain B cell lymphomas by highlighting B cells within tissue sections using the immunohistochemistry method. The presence of BOB-1 can be an important factor in determining the nature of lymphoproliferative disorders.

Special Instructions

Not provided.

Limitations

This test has not been cleared or approved by the FDA and is considered a laboratory-developed test (LDT). The assay is intended for use in a clinical laboratory setting and the interpretation of results should be made within the context of the larger clinical picture. The staining and interpretation require professional expertise and the test is performed as a stain and return (technical) service only, meaning no clinical interpretation is provided as part of the service.

Test Details

New York Approved

Methodology

Immunoassay (IHC)

Biomarkers

BOB-1

Protein

IHC

Expression • Ordinal Score (e.g., TPS, CPS, H-score)

LOINC Codes

Order Codes

53637-5 - BOB1 Ag Tiss Ql ImStn

Result Codes

94736-6 - Tissue block ID Spec

Result Turnaround Time

1-3 days

Specimen

Tissue (FFPE)

Volume

Not provided

Minimum Volume

2 slides

Container

Paraffin block or 5 unstained positively charged slides

Collection Instructions

Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen (cells must be prepared into a cellblock). Protect paraffin block and/or slides from excessive heat. Transport tissue block or 5 unstained (3- to 5-micron thick sections), positively charged slides in a tissue transport kit (ARUP supply #47808).