Chromosome Analysis, Leukemic Blood with Reflex to Genomic Microarray
Also known as: LKB REFLEX
Use
This test is used for the diagnosis, prognosis, and monitoring of hematopoietic neoplasms. It includes a Chromosome Analysis to detect abnormalities in chromosome structure or number. If the karyotype is normal or there's no growth, the test reflexes to a Genomic Microarray (Oligo-SNP Array), which provides a higher resolution analysis for detecting micro-deletions or duplications that may not be visible under a microscope.
Special Instructions
Not provided.
Limitations
This test may not detect all chromosomal rearrangements or mutations. Certain genomic alterations, including CNVs below the platform's resolution, point mutations, indels, balanced chromosomal rearrangements, and low-level mosaicism may not be detected. The detection sensitivity varies based on tumor content and genomic region complexity.
Methodology
Chromosomal / Cytogenetics
Biomarkers
LOINC Codes
- 62357-9 - Chrom analy overall interp-Imp
Result Turnaround Time
3-21 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL
Minimum Volume
1 mL
Container
Green (sodium heparin) tube
Storage Instructions
Do not freeze or expose to extreme temperatures. Transfer to the appropriate container and store at room temperature.
Causes for Rejection
Clotted specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 48 hours |
| Frozen | Unacceptable |
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