DOG1 by Immunohistochemistry
Also known as: DOG1 IHC
Use
Screening test in tumor that is morphologically and clinically suspicious for gastrointestinal stromal tumor (GIST) when CD117 is negative.
Special Instructions
Not provided.
Limitations
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. It was performed in a CLIA‑certified laboratory and is intended for clinical purposes.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
DOG1
Protein
LOINC Codes
- 94736-6 - Tissue block ID Spec
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen (cells must be prepared into a cellblock). Transport tissue block or 5 unstained (4‑micron thick sections), positively charged slides in a tissue transport kit (ARUP supply #47808 recommended but not required). Min: 3 slides. If sending precut slides, do not oven bake.
Storage Instructions
Room temperature or refrigerated; ship in cooled container during summer months.
Causes for Rejection
Specimens submitted with non‑representative tissue type. Depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |
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