Epithelial Membrane Antigen (EMA) by Immunohistochemistry
Also known as: EMA IHC
Use
The Epithelial Membrane Antigen (EMA) by Immunohistochemistry is used as a stain in diagnostic pathology to identify the presence of epithelial cells in tissue samples. EMA is commonly used to help differentiate between epithelial and non-epithelial neoplasms. This test serves as an important tool in characterizing tumors and assessing their histological origin, aiding in the diagnostic process and informing treatment decisions.
Special Instructions
Submit electronic request for immunohistochemistry ordering. If electronic ordering capability is unavailable, use an ARUP Immunohistochemistry Stain Form (#32978) with an ARUP client number. Ensure specimens are formalin-fixed and paraffin-embedded. Use ARUP supply #47808 for transport. Contact ARUP Client Services for further assistance.
Limitations
This test is performed as a stain and return (technical) service only. It is important to protect the paraffin block and slides from excessive heat. Specimens submitted with non-representative tissue type or depleted specimens are unacceptable. Ambient and refrigerated stability is indefinite, but frozen specimens are not acceptable.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 94736-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
2 slides
Container
Tissue transport kit (ARUP supply #47808)
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen. Transport tissue block or 5 unstained, positively charged slides.
Storage Instructions
Room temperature or refrigerated. Ship in cooled container during summer months.
Causes for Rejection
Specimens submitted with non-representative tissue type. Depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |