Neurofilament by Immunohistochemistry
Also known as: NEUROF IHC
Use
The Neurofilament by Immunohistochemistry test is utilized to detect neurofilament proteins within tissue samples. This type of analysis is useful for identifying neuronal elements in various tissue specimens, particularly in the diagnosis of neural tumors and related pathologies. The presence of neurofilaments can help differentiate neuronal tissue from other tissue types, aiding in the identification of neural tumors and evaluating the integrity of nervous system structures.
Special Instructions
Immunohistochemistry ordering requires submission of an electronic request. If you do not have electronic ordering capability, use an ARUP Immunohistochemistry Stain Form with an ARUP client number. For technical assistance, contact ARUP Client Services.
Limitations
This test is conducted as a stain and return service only, meaning it is performed for technical purposes rather than providing interpretative diagnostics. It is not applicable for specimens that lack representative tissue or are depleted. Additionally, it is unsuitable for frozen specimens, as these conditions are considered unacceptable.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 94736-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Tissue transport kit (ARUP supply #47808)
Collection Instructions
Collect tissue or cells. Formalin fix (10 percent neutral buffered formalin) and paraffin embed the specimen. Transport tissue block or 5 unstained (3- to 5-micron thick sections), positively charged slides.
Storage Instructions
Room temperature or refrigerated. Ship in cooled container during summer months.
Causes for Rejection
Non-representative tissue type. Depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |