Zinc Transporter 8 Antibody
Also known as: ZNT8 AB
Use
The Zinc Transporter 8 antibody test is most useful for establishing autoimmune etiology in patients with previously diagnosed type 1 diabetes mellitus (DM). It should not be used to differentiate between type 1 and type 2 DM for most cases. When pursuing antibody testing to determine autoimmune DM, it is recommended to perform at least two antibody tests. Typically, the glutamic acid decarboxylase antibody is used in conjunction with another antibody test, such as Islet Antigen-2 (IA-2) Autoantibody, Glutamic Acid Decarboxylase Antibody, Insulin Antibody, or Islet Cell Cytoplasmic Antibody, IgG, to increase diagnostic accuracy.
Special Instructions
Not provided.
Limitations
This test is not suitable for differentiating between type 1 and type 2 diabetes mellitus in most cases. The assay determines the presence of antibodies to Zinc Transporter 8 in human serum in a semi-quantitative manner. The results should be interpreted within the context of accompanying clinical symptoms. Reference intervals are 0.0-15.0 Kronus Units/mL, with values above 15.0 indicating a positive test for ZnT8 antibodies.
FDA ApprovedNew York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
Zinc Transporter 8
Antibody
LOINC Codes
- 76651-9 - ZnT8 Ab SerPl IA-aCnc
Result Turnaround Time
1-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.1 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Collect in serum separator tube or plain red. After separation from cells, transfer serum to transport tube.
Storage Instructions
Refrigerated
Causes for Rejection
Plasma; severely lipemic or grossly hemolyzed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 5 days |
| Refrigerated | 1 week |
| Frozen | 3 months |
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