Oncology FISH Analysis - STAT AML FISH Panel
Use
Oncology FISH Analysis – STAT AML FISH Panel is specifically designed for detecting chromosomal abnormalities associated with acute myeloid leukemia (AML), a type of leukemia primarily affecting adults. The test identifies several translocations and rearrangements that can be critical for diagnostic and prognostic purposes. Abnormalities such as t(8;21)(q22;q22) and KMT2A rearrangements are found in varying percentages of AML cases and have implications on treatment outcomes. Results must always be interpreted in conjunction with clinical data, emphasizing the importance of this assay in effectively managing AML patients.
Special Instructions
This test is particularly indicated for patients with suspected AML, providing insights for prognostic evaluation and monitoring of treatment response. Interpretation of results requires clinical correlation with relevant pathological data to avoid misdiagnosis. FISH analysis ensures targeted detection of specific abnormalities that may influence treatment decisions.
Limitations
This assay exclusively tests for specific chromosomal abnormalities and cannot identify other potential abnormalities outside the specified loci. It is critical to note that results derived from this test should not serve as standalone diagnostic criteria, but rather as supplementary data for comprehensive clinical evaluations and decisions.
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Bone Marrow (Unknown)
Volume
3-5 cc
Minimum Volume
2 cc
Container
sodium heparin (green-top) tube
Collection Instructions
Draw bone marrow in sodium heparin (green-top) tube(s) and send 3-5 cc (adults/children) or 2 cc (infant<2 years).
Storage Instructions
Ship at ambient temperature (18-25°C/64-77°F) in an insulated container by overnight courier.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |