Acute Lymphoblastic Leukemia (ALL) Panel by FISH, Adult

Casandra

Casandra Test Code AR74813Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 2002647CPT Codes 88271, 88275

Acute Lymphoblastic Leukemia (ALL) Panel by FISH, Adult

Also known as: FISH A ALL

Clinical Use

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Use

The Acute Lymphoblastic Leukemia (ALL) Panel by FISH is designed for adults with newly diagnosed ALL. It is used to detect recurrent genetic abnormalities through rearrangements, providing information helpful in the diagnosis, prognosis, and treatment decisions for patients with ALL. FISH testing can identify specific chromosomal changes associated with ALL, potentially guiding therapeutic choices and risk stratification.

Special Instructions

A processing fee will apply if the procedure is canceled after setup or if sample integrity is inadequate. Other specimen types may be acceptable; contact the Cytogenetics Laboratory for specific instructions. This test must be ordered using Oncology test request form #43099 or through the ARUP interface. If multiple FISH tests are ordered, processing fees will only be applied once. Ensure that the ordering includes the clinical indication and specimen type.

Limitations

Paraffin-embedded specimens and clotted specimens are unacceptable. Stability is limited to 48 hours at ambient or refrigerated temperatures; samples frozen are unacceptable. While FISH can detect certain chromosomal rearrangements, some potential partners for these rearrangements may not be identified, which limits the interpretability of rearrangement results.

Test Details

New York Approved