11-Deoxycortisol
Also known as: 11-Desoxycortisol, Compound S for Metyrapone Test
Use
Evaluate hypothalamic-pituitary-adrenal axis and pituitary ACTH reserve
Special Instructions
Not provided.
Limitations
A reduced response to the metyrapone test occurs in patients with hypoadrenalism or hypopituitarism and in some patients with diseases of the hypothalamus. Patients with myxedema, some pregnant patients, and those on oral contraceptives may respond poorly. Recently administered isotopes may cause test interference, leading to rejection of the sample.
Methodology
Mass Spectrometry
Biomarkers
11-Deoxycortisol
Analyte
LOINC Codes
- 1657-6 - 11DC SerPl-mCnc
- 1657-6 - 11DC SerPl-mCnc
Result Turnaround Time
6-10 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.2 mL
Container
Red-top tube or gel-barrier tube
Collection Instructions
Transfer the serum into a LabCorp PP transpak frozen purple tube with screw cap (LabCorp N° 49482). Freeze immediately and maintain frozen until tested.
Patient Preparation
No isotopes administered 24 hours prior to venipuncture
Storage Instructions
Freeze.
Causes for Rejection
Recently administered isotopes
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 1 day |
| Refrigerated | 1 day |
| Frozen | 2 years |
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