ALK FISH, Non-Small-cell Lung Cancer
Also known as: Non Small Cell Lung Cancer FISH, NSCLC ALK FISH, Oncology FISH
Use
Confirmation/identification of non-small-cell lung cancer (this is a test for the identification of NSCLC patients who may be eligible for treatment); qualitative/quantitative evaluation of ALK rearrangement
Special Instructions
Not provided.
Limitations
Molecular mutations or chromosomal alterations not targeted by the probe included in this profile will not be detected. Suboptimal pre-analytic conditions, including improper fixation times or methods, cold ischemia time outside recommended guidelines, and tissue decalcification, may negatively impact results. Genetic changes other than those assayed here cannot be ruled out based on this testing.
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
LOINC Codes
- 66746-9 - Specimen type
- 64089-6 - Cells counted CVS
- 64086-2 - Cells analyzed CVS
- 78233-4 - Cells.ALK rear/Cells cnt NFr Bld/T FISH
- 78210-2 - ALK rearrange Bld/T FISH-Imp
- 48672-0 - Clinical cytogeneticist Spec
- 11502-2 - Laboratory report
- 66746-9 - Specimen type
- 64089-6 - Cells counted CVS
- 64086-2 - Cells analyzed CVS
- 78233-4 - Cells.ALK rear/Cells cnt NFr Bld/T FISH
- 78210-2 - ALK rearrange Bld/T FISH-Imp
- 48672-0 - Clinical cytogeneticist Spec
- 11502-2 - Laboratory report
Result Turnaround Time
4-7 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Five slides (4- to 5-micron) on positively charged slides or one paraffin block
Minimum Volume
Two slides (4- to 5-micron thick sections) on positively charged slides or one paraffin block
Container
Paraffin block
Collection Instructions
Utilize sterile technique and Labcorp transport kits when possible.
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Tumor other than lung; use of fixatives other than 10% formalin; improper embedded prep; poor fixation 72 hours; decalcified bones or bone core; absence of tumor or quantity not sufficient for analysis
Other tests from different labs that may be relevant