Allergen Profile, Cat, Dog and Horse, IgE With Component Reflex

Casandra

Casandra Test Code LC43147Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 607016CPT Code 86003

Allergen Profile, Cat, Dog and Horse, IgE With Component Reflex

Clinical Use

Use

Allergen component testing offers advantages over the use of a complete extract, especially in poly-sensitized individuals, given its usefulness for distinguishing between sensitizations specific to singular species and sensitizations due to cross-reactivity.

Special Instructions

If Cat IgE is ≥0.35 kU/L, Fel d 1 IgE, Fel d 2 IgE, Fel d 4 and Fel d 7 IgE testing will be performed. For Dog IgE ≥0.35 kU/L, additional testing for Can f 1, Can f 2, Can f 3, Can f 4, Can f 5, and Can f 6 IgE will occur. If Horse IgE is ≥0.35 kU/L, Equ c 1 IgE will be tested.

Limitations

This test cannot identify all possible allergenic proteins and does not replace detailed clinical evaluation. The possibility of cross-reactivity among different mammalian species could lead to positivity in the absence of direct sensitization. The presence of specific IgE needs to be interpreted in conjunction with a patient’s clinical history due to potential for cross-reactivity causing misidentification.

Test Details