Anti-Glomerular Basement Membrane Antibodies (RDL)
Also known as: Anti-Glomerular Basement Membrane Ab
Use
Anti-GBM autoantibodies are recognized as being important in the pathogenesis of the rapidly progressive glomerulonephritis of Goodpasture's syndrome. Detects the presence of circulating glomerular basement membrane-specific antibodies in autoimmune renal disorders such as Goodpasture's syndrome.
Special Instructions
For serum specimen, it is important to separate serum from cells within one hour of collection and transfer to a plastic transport tube before shipping. This will help avoid delays, especially if multiple tests on frozen samples are requested. Separate frozen specimens should be submitted for each test requested.
Limitations
Test results may be affected by specimen quality. Grossly hemolyzed, lipemic, icteric specimens, or those with bacterial contamination, as well as non-serum specimen types, may be rejected. Repeat testing is not possible with the minimum volume, and additional time should be considered for confirmatory or reflex tests.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 49774-3
- 49774-3
Result Turnaround Time
7-14 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Red-top tube or gel-barrier tube
Collection Instructions
Separate serum from cells within one hour of collection and transfer to a plastic transport tube before shipping.
Storage Instructions
Refrigerate or freeze.
Causes for Rejection
Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 60 days |