Glomerular Basement Membrane Antibody, IgG by Multiplex Bead Assay
Also known as: GBM-G ELIS
Use
The presence of anti-glomerular basement membrane (GBM) antibodies by multiplex bead assay may aid in the diagnosis of Goodpasture syndrome. This test is useful in detecting GBM antibodies. If positive, it may be useful for monitoring treatment response and diagnostic confirmation in suspected Goodpasture disease with renal involvement.
Special Instructions
The combined use of IFA Glomerular Basement Membrane Antibody, IgG by Multiplex Bead Assay and IFA (2008403) may improve diagnostic sensitivity for disease.
Limitations
False-positive results may occur due to reactivity against other chains of type IV collagen. If the multiplex bead assay is negative but there is strong suspicion for disease, a renal biopsy may be indicated.
New York Approved
Methodology
Other
Biomarkers
LOINC Codes
- 44446-3
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.15 mL
Container
ARUP standard transport tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP standard transport tube.
Storage Instructions
Refrigerated.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year (avoid repeated freeze/thaw cycles) |