Antiglomerular Basement Membrane Antibodies
Also known as: glomerulonephritis, Goodpasture pulmo-renal Syndrome, Goodpasture Syndrome
Use
Anti-GBM antibodies (glomerular basal membrane; Goodpasture Antigen) are important for the diagnosis of glomerulonephritis, which may be accompanied by pulmonary hemorrhage (Goodpasture pulmo-renal Syndrome). Due to clinical symptoms similar with systemic vasculitis, it is appropriate to concurrently carry out tests for anti-GBM and antineutrophil cytoplasmic antibodies (ANCA).
Special Instructions
It is recommended to conduct tests for anti-GBM and antineutrophil cytoplasmic antibodies (ANCA) concurrently due to the similarity in clinical symptoms with systemic vasculitis.
Limitations
The test may not be sufficient for a conclusive diagnosis of glomerulonephritis if not performed alongside additional tests for systemic vasculitis. Also, the results need careful interpretation as other conditions might mimic the symptoms of glomerulonephritis.
Methodology
Immunoassay (Multiplex Protein Panel)
Biomarkers
LOINC Codes
- 59394-7
- 59394-7
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.6 mL
Minimum Volume
0.3 mL
Container
Red-top tube or gel-barrier tube
Storage Instructions
Room temperature
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |