Use

Anti-histidyl-tRNA synthetase autoantibodies are the most common Myositis Specific Antibodies (MSA), comprising 30-40% of Idiopathic Inflammatory Myopathies (IIM), although OJ specifically is seen in less than 5% of IIM. Anti-Synthetase antibodies can be found in polymyositis, dermatomyositis or overlap myositis. Symptoms associated with these antibodies include non-erosive arthritis, ILD, fever, mechanic's hands and Raynaud's.