Anti-Ro, Total (Combined Anti-SS-A 52 kD and Anti-SS-A 60 kD Together)
Also known as: RO Ab, SSA Ab, SSA/RO Ab
Use
Anti-Ro (SS-A) antibodies occur in 40-50% of SLE, 60-75% of primary Sjogren's syndrome (PSS) and in a high proportion of secondary SS whether the associated disease is in SLE, RA, PSS, polydermato-myositis, or primary biliary cirrhosis, but is >90% of subacute cutaneous lupus and in vasculitis-associated SS.
Special Instructions
Separate serum from cells within one hour of collection and transfer to a plastic transport tube before shipping. Ensure separate frozen specimens for each test if multiple tests are requested.
Limitations
This test does not differentiate anti-Ro52 and anti-Ro60 antibodies. Individual measurements of anti-Ro52 and anti-Ro60 will not additively equal the total Ro result. A negative result does not exclude autoimmune disease. The anti-Ro profile provides individual results for anti-Ro52 and anti-Ro60, and results should always be interpreted alongside other lab and clinical findings.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 33569-5
- 33569-5
Result Turnaround Time
5-7 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Red-top tube or gel-barrier tube
Collection Instructions
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.
Storage Instructions
Refrigerate or freeze.
Causes for Rejection
Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 60 days |