Bilirubin, Total and Direct
Also known as: Bilirubin, Total, Conjugated, and Unconjugated
Use
Liver and biliary tests are useful in the differential diagnosis of jaundice from bilirubin overproduction (hemolysis), decreased uptake (Gilbert disease), decreased conjugation (hepatocellular disease, familial, drug-induced, pregnancy; obstructive bile duct disease).
Special Instructions
Not provided.
Limitations
The accuracy of this test may be impacted by specimen handling and processing times. Severe hemolysis, improper labeling, or severe lipemia can render the specimen unsuitable for analysis. Additionally, variations in testing schedules or requirements for additional confirmatory tests may affect result turnaround time.
Methodology
Automated Analyzer (Clinical Chemistry)
Biomarkers
Bilirubin, Direct
AnalyteBilirubin, Indirect
AnalyteBilirubin, Total
Analyte
LOINC Codes
- 34543-9 - Bilirubin Direct+Tot Pnl SerPl-mCnc
- 1975-2 - Bilirub SerPl-mCnc
- 1968-7 - Bilirub Direct SerPl-mCnc
- 1971-1 - Bilirub Indirect SerPl-mCnc
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3 mL
Minimum Volume
1 mL
Container
Red-top tube, gel-barrier tube, or green-top (lithium heparin) tube
Collection Instructions
Separate serum or plasma from cells within 45 minutes of collection.
Storage Instructions
Refrigerate
Causes for Rejection
Severe hemolysis; improper labeling; severe lipemia
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 2 days |
| Refrigerated | 3 days |
| Frozen | 14 days |
Other tests from different labs that may be relevant