Ethanol, Whole Blood
Also known as: Alcohol, Blood, Blood Alcohol Level, Ethyl Alcohol, Blood
Use
Quantitation of alcohol level for medical or legal purposes; test unconscious patients; used to diagnose alcohol intoxication and determine appropriate therapy; detect alcoholism and to monitor ethanol treatment for methanol intoxication. Must be tested as possible cause of coma of unknown etiology since alcohol intoxication may mimic diabetic coma, cerebral trauma, and drug overdose.
Special Instructions
Do not prepare venipuncture site with alcohol or remove stopper from tube.
Limitations
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration. Ethanol is absorbed rapidly from the GI tract. Peak blood levels usually occur within 40 to 70 minutes on an empty stomach. Food in the stomach can decrease the absorption of alcohol. Ethanol is metabolized by the liver to acetaldehyde. Once peak blood ethanol levels are reached, disappearance is linear; a 70 kg man metabolizes 7−10 g of alcohol/hour (15±5 mg/dL/hour). The urine:blood ratio is considered to be about 1.35:1 but is quite variable. The average saliva:blood ratio is 1:20. Symptoms of intoxication in the presence of low alcohol levels could indicate a serious acute medical problem requiring immediate attention. The half-lives and effectiveness of certain drugs (e.g., barbiturates) are increased in the presence of ethanol.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 56478-1
- 56478-1
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
7 mL
Minimum Volume
0.5 mL
Container
Gray-top (sodium fluoride) tube (preferred) or red-top tube. Submit original unopened tube. Do not centrifuge and separate serum if a red-top tube is submitted.
Storage Instructions
Room temperature
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |