Hepatitis B Core Antibody, Total With Reflex to IgM

Also known as: anti-HBc, anti-HBc Total and IgM, HBV

Clinical Use

Use

This assay can be used as an aid in the diagnosis of individuals with acute or chronic hepatitis B virus (HBV) infection and in the determination of the clinical status of HBV infected individuals in conjunction with other HBV serological markers for the laboratory diagnosis of HBV disease associated with HBV infection. This assay can also be used as an aid in the differential diagnosis in individuals displaying signs and symptoms of hepatitis in whom etiology is unknown. This panel can be used to differentiate between the presence of anti-HBc IgG and IgM.

Special Instructions

Not provided.

Limitations

The results from this or any other diagnostic kit should be used and interpreted only in the context of the overall clinical picture. A negative test result does not exclude the possibility of exposure to hepatitis B virus. Levels of anti-HBc may be undetectable both in early infection and late after infection. This qualitative assay cannot correlate reported antibody levels to an endpoint titer. Performance characteristics have not been established for immunocompromised or immunosuppressed patients.

Test Details

Methodology

Immunoassay (CLIA)

Biomarkers

Hep B Core Ab, IgM

Protein

IgM

Other • Binary (Detected / Not Detected)

Hep B Core Ab, Total

Protein

Total

Other • Binary (Detected / Not Detected)

LOINC Codes

Order Codes

13952-7 - HBV core Ab SerPl Ql IA

Result Codes

13952-7 - HBV core Ab SerPl Ql IA
24113-3 - HBV core IgM SerPl Ql IA

Result Turnaround Time

1-3 days

Specimen

Serum

Volume

1 mL

Minimum Volume

0.5 mL

Container

Gel-barrier tube, red-top tube or serum transfer tube

Collection Instructions

If tube other than a gel-barrier tube is used, transfer separated serum to a screw-cap polypropylene transport tube. Do not freeze gel-barrier tube (pour off serum first).