Hepatitis B Surface Antibody, Qualitative
Also known as: Anti-HBs, Antibody to Hepatitis B Surface Antigen, HBV
Use
Presence of antibody to hepatitis B surface antigen (anti-HBs) is used to determine immune status to HBV or disease progression in individuals infected with HBV. Anti-HBs levels can be measured to determine if vaccination is needed, or following a vaccination regimen, to determine if protective immunity has been achieved.
Special Instructions
Not provided.
Limitations
Presence of anti-HBs is not an absolute indicator of resolved hepatitis infection, nor of protection from future infection. Since there are different serologic subtypes of hepatitis B virus, it is possible for a patient to have antibody to one surface antigen type and to be acutely infected with virus of a different subtype. Transfused individuals or hemophiliacs receiving plasma components may give false-positive tests for antibody to hepatitis B surface antigen.
Methodology
Immunoassay (CLIA)
Biomarkers
Hepatitis B Surface Antigen
Protein
LOINC Codes
- 22322-2 - HBV surface Ab Ser Ql
- 22322-2 - HBV surface Ab Ser Ql
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.3 mL
Container
Gel-barrier tube or red-top tube
Collection Instructions
If tube other than a gel-barrier tube is used, transfer separated serum to a screw-cap polypropylene transport tube. Do not freeze gel-barrier tube (pour off serum first).
Storage Instructions
Room temperature
Causes for Rejection
Cadaver specimens; heat-inactivated specimens; body fluids other than serum or plasma
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
Other tests from different labs that may be relevant