Mitochondrial (M2) Antibody
Also known as: AMA
Use
The presence of mitochondrial antibodies can be used in conjunction with clinical findings and other laboratory tests to aid in the diagnosis of primary biliary cirrhosis (PBC).
Special Instructions
Not provided.
Limitations
The presence of immune complexes in the patient's sample may cause an increased level of nonspecific binding and produce false-positive results. Not all PBC patients are positive for mitochondrial antibodies. Results should be used in conjunction with clinical findings and other serologic tests.
Methodology
Immunoassay (ELISA)
Biomarkers
Mitochondrial (M2) Antibody
Antibody
LOINC Codes
- 49781-8 - Mitochondria M2 Ab Ser-aCnc
- 49781-8 - Mitochondria M2 Ab Ser-aCnc
Result Turnaround Time
2-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Red-top tube or gel-barrier tube
Storage Instructions
Room temperature
Causes for Rejection
Hemolysis; lipemia; gross bacterial contamination; heat-treated specimen; specimen with preservative added
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
Other tests from different labs that may be relevant