Use

The G‑nAChR autoantibody assay identifies autoantibodies to the ganglionic (alpha‑3) nicotinic acetylcholine receptor. It aids in diagnosing autoimmune autonomic ganglionopathy (AAG), differentiating immunotherapy‑responsive AAG from idiopathic autonomic neuropathy. Elevated antibody levels may suggest a paraneoplastic cause—particularly small‑cell lung cancer or thymoma—where detection can lead to focused tumor evaluation and immunologic treatment and improved outcomes. ([jdos.nicholsinstitute.com](https://jdos.nicholsinstitute.com/dos/BPMC/test/538647?utm_source=openai))