Beta‑2‑Glycoprotein I Antibodies (IgG, IgA, IgM)
Use
Measures antibodies of immunoglobulin classes IgG, IgA, and IgM that target beta‑2‑glycoprotein I, aiding in evaluation of antiphospholipid syndrome—an autoimmune clotting disorder associated with thrombosis risk and pregnancy loss. It supports diagnosis of APS, investigation of unexplained thrombotic events (e.g., DVT, stroke, PE), recurrent pregnancy loss, and monitoring of autoimmune conditions such as lupus.
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
Immunoassay
Biomarkers
B2 Glycoprotein I (IgA) Ab
AnalyteB2 Glycoprotein I (IgG) Ab
AnalyteB2 Glycoprotein I (IgM) Ab
Analyte
Result Turnaround Time
4-6 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
3 mL
Minimum Volume
1.5 mL
Container
Light Blue (Sodium Citrate) tube; Red‑top tube acceptable
Collection Instructions
Collect (two‑four) 1.8 mL or (two‑three) 2.7 mL blood in light blue tube; serum: centrifuge red‑top tube within 24 h; process platelet‑poor plasma by two spins, avoiding buffy coat
Causes for Rejection
Gross hemolysis; grossly lipemic
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 5 Days |
| Refrigerated | 14 Days |
| Frozen | 30 Days |
Other tests from different labs that may be relevant