Fecal Globin by Immunochemistry (InSure®)
Also known as: FOBT, Occult Blood, Guaiac, FOB, FIT
Use
InSure® ONE is a fecal immunochemical test (FIT) that qualitatively detects human hemoglobin from blood in fecal samples to aid in detection of lower gastrointestinal bleeding, including that which may be caused by colorectal cancer, large adenomas, polyps, diverticulitis, or ulcerative colitis. It supports early detection of colorectal cancer and other bleeding-related lower gastrointestinal disorders, with guideline support from organizations such as the American Cancer Society, American College of Gastroenterology, and the US Preventive Services Task Force.([clinical.questdiagnostics.com](https://clinical.questdiagnostics.com/QuestInsureONE?utm_source=openai))
Special Instructions
Not provided.
Limitations
No dietary or medicinal restrictions interfere with this assay, unlike guaiac-based tests. Only a qualitative result is provided, and it does not specify lesion location or quantify bleeding. Not a substitute for colonoscopy following a positive result.([rchsd.org](https://www.rchsd.org/lab-test/fecal-globin-by-immunochemistry-insure-11290/?utm_source=openai))
Methodology
Immunoassay (Immunochromatography)
Biomarkers
Fecal Globin
Analyte
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Stool
Volume
Not provided
Minimum Volume
Not provided
Container
InSure FOBT Test Card
Collection Instructions
Collect stool sample from toilet water by brushing and apply to 1–2 windows on the InSure FOBT test card; brushed onto the test card.
Patient Preparation
No special diet or avoidance of drugs or supplements required.
Causes for Rejection
Stool submitted in any container; InSure FOBT cards with stool applied to the sample windows; any test card with obvious blood present; submitted refrigerated or frozen.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 Days |
| Refrigerated | Unacceptable |
| Frozen | Unacceptable |
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