First Trimester Screen, hCG

Casandra

Casandra Test Code QD77194Version 1 (DRAFT)

Performing Lab

Lab Quest DiagnosticsLab Test ID 16145

First Trimester Screen, hCG

Also known as: Human Chorionic Gonadotropin (hCG), Nuchal Translucency (NT), Down Syndrome, Trisomy 18 Screen, MSS

Clinical Use

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Use

This test is used for first‑trimester screening of fetal aneuploidy—specifically for Down syndrome (trisomy 21) and trisomy 18—by combining biochemical markers with nuchal translucency measurement to assess risk.

Special Instructions

Includes measurement of PAPP‑A, hCG, and nuchal translucency, with risk assessments and interpretation. Ordered during the first trimester of pregnancy.

Limitations

Not provided.

Test Details

Methodology

Immunoassay (Multiplex Protein Panel)

Biomarkers

hCG

Analyte

hCG • Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

PAPP-A

Analyte

PAPP-A • Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

Result Turnaround Time

0 days

Specimen

Serum

Volume

Not provided

Minimum Volume

Not provided

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