Casandra
Casandra Test Code QD05283Version 1 (DRAFT)
Performing Lab
FISH, CLL, CEP 12, Trisomy 12
Clinical Use
Order TestUse
Fluorescence in situ hybridization (FISH) targeting centromere of chromosome 12 (CEP 12) is used to detect trisomy 12 in patients with chronic lymphocytic leukemia (CLL), providing prognostic information relevant for diagnosis and disease monitoring.
Special Instructions
Clinical history or reason for referral is required at test order; prior therapy and transplant history should also be provided. Viability decreases during transit; specimen must not be frozen. Do not reject unless viability is determined poor. Transport at room temperature.
Limitations
Not provided.
Test Details
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Unknown CNV
Copy Number RegionCopy Number • Categorical (e.g., Positive / Negative / Indeterminate)
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Bone Marrow
Volume
3 mL
Minimum Volume
1 mL
Container
sodium heparin (green‑top) tube
Storage Instructions
Do not freeze; room temperature