Casandra
Casandra Test Code QD76302Version 1 (DRAFT)
Performing Lab
FISH, Follicular Lymphoma, IGH/BCL2, t(14;18)
Clinical Use
Order TestUse
Translocation t(14;18)(q32;q21.3) is assayed by FISH with probes from the regions IGH (14q32) and BCL2 (18q21.3). This assay is useful to diagnose follicular lymphoma (present in >75% of cases) and diffuse large cell lymphomas (~25%). This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics, validated under CLIA regulations. ([jdos.nicholsinstitute.com](https://jdos.nicholsinstitute.com/dos/prismahealth/test/909328?utm_source=openai))
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
Chromosomal / Cytogenetics
Biomarkers
Unknown CNV
Copy Number RegionIGH probe • Copy Number • Categorical (e.g., Positive / Negative / Indeterminate)
Unknown CNV
Copy Number RegionBCL2 probe • Copy Number • Categorical (e.g., Positive / Negative / Indeterminate)
Result Turnaround Time
Not provided.
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Whole Blood
Volume
5 mL
Minimum Volume
1 mL
Container
sodium heparin (green-top), royal blue-top or tan-top tube
Collection Instructions
Do not freeze. Send at room temperature.