Herpes Simplex Virus Type 1 and 2, IHC with Interpretation
Use
For the detection of HSV‑infected tissue. Two serotypes of the herpes simplex virus, HSV‑1 (also known as type 1 or oral) and HSV‑2 (type 2 or genital), can establish lifelong latent infections with sensory ganglia. Periodically, the virus reactivates and can cause recurrent cold sores, encephalitis and eye and genital infections. HSV‑1 usually establishes latency in the trigeminal ganglion, a collection of nerve cells near the ear. From there, it tends to recur on the lower lip or face. HSV‑2 usually resides in the sacral ganglion at the base of the spine. From there, it reiterates in the genital area.
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Formalin‑fixed, paraffin‑embedded tissue block submitted in an IHC Specimen Transport Kit; minimum: 3 unstained, positively charged slides; do not freeze; include surgical pathology report
Storage Instructions
Room temperature indefinitely
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |
