Myelin Oligodendrocyte Glycoprotein (MOG) Antibody, with Reflex to Titer, Serum
Also known as: Transverse Myelitis Antibody, MOG-IgG, Myelin oligodendrocyte glycoprotein, NMO Spectrum Disorder, LETM antibody
Use
The Myelin Oligodendrocyte Glycoprotein (MOG) Antibody test is used to detect the presence of MOG antibodies in serum, which can be associated with idiopathic inflammatory demyelinating diseases, including neuromyelitis optica spectrum disorders.
Special Instructions
Testing includes an initial screen for MOG antibodies. If positive, a titer is reflexively performed to determine antibody levels. This test is pertinent for diagnosing and management of patients with demyelinating disorders.
Limitations
This test may not distinguish between different types of demyelinating diseases and should be interpreted in conjunction with clinical findings and other laboratory tests. False positives and negatives can occur, particularly in the presence of other autoimmune conditions.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
Result Turnaround Time
7-10 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL
Container
Red-top tube or serum gel tube
Collection Instructions
Collect blood into a red-top or serum gel tube. Allow to clot and then centrifuge to separate serum.
Storage Instructions
Store and send serum frozen.
Causes for Rejection
Gross hemolysis; lipemia
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 48 hours |
| Frozen | 14 days |