Myeloperoxidase Antibody (MPO)
Also known as: Anti-Myeloperoxidase, Churg-Strauss Syndrome, Crescentic Glomeruloephritis, MPO
Use
Autoimmune vasculitis diseases are characterized by abnormal immune responses that result in inflammation and necrosis of blood vessels. The immune dysfunction may be triggered by infection, autoimmune disease, or exposure to a drug; often the cause is unknown. ANCA‑associated vasculitis diseases are often characterized by the size of the blood vessels involved. The diseases present with diverse clinical features and are often rapidly progressive, causing irreversible injury to the vessels of the organs affected, such as the kidneys and lungs.
Special Instructions
Not provided.
Limitations
Approximately 90% of patients with a P‑ANCA pattern by IFA have myeloperoxidase‑specific antibodies.
Methodology
Immunoassay (IA)
Biomarkers
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1‑2 mL serum
Minimum Volume
0.3 mL
Container
Red Top (No Additive)
Collection Instructions
Avoid hemolysis.
Causes for Rejection
Gross hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 30 days |
