Casandra
Casandra Test Code QD35322Version 1 (DRAFT)
Performing Lab
NMO Spectrum Evaluation (AQP4 with Reflex to MOG), Serum
Also known as: Transverse Myelitis Antibody, NMO antibody, Aquaporin, Optic Neuritis Antibody, NMO-IgG
Clinical Use
Order TestUse
Evaluation for neuromyelitis optica spectrum disorder (NMOSD) via detection of aquaporin‑4 (AQP4) antibodies in serum, with reflex to MOG antibodies if AQP4 is negative. This aids in distinguishing NMOSD from multiple sclerosis by identifying AQP4-associated disease or MOG antibody–associated disorder, ensuring proper diagnosis and guiding appropriate immunotherapy.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
Immunoassay (Cell‑based Immunoassay)
Biomarkers
2 components
AQP4 Antibody Screening • Cell‑based ImmunoassayMOG Antibody Reflex • Cell‑based Immunoassay
Result Turnaround Time
Not provided.
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL
Container
red-top tube (no gel)
Causes for Rejection
Gross hemolysis; grossly lipemic; serum separator tube (SST)
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 21 days |
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