Beta-2 Microglobulin, CSF
Also known as: B2M CSF
Use
The Beta-2 Microglobulin, CSF test is used to evaluate involvement of the central nervous system in certain inflammatory or B-cell proliferative diseases. Elevated levels of Beta-2 Microglobulin in the cerebrospinal fluid (CSF) can indicate an active disease process affecting the central nervous system. This test is particularly useful in the assessment of diseases like multiple sclerosis and central nervous system involvement in systemic lupus erythematosus.
Special Instructions
Not provided.
Limitations
Beta-2 Microglobulin, CSF levels may be influenced by factors other than central nervous system diseases, such as systemic inflammation or renal impairment, which can result in elevated levels. These conditions may confound the interpretation of test results. Additionally, this test, developed and its performance determined by ARUP Laboratories, has not been cleared or approved by the US FDA, although it is performed in a CLIA-certified laboratory.
New York Approved
Methodology
Immunoassay (Quantitative Immunoturbidimetry)
Biomarkers
Beta-2 Microglobulin
Protein
LOINC Codes
- 1951-3 - B2 Microglob CSF-mCnc
Result Turnaround Time
0-1 day
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
0.5 mL
Minimum Volume
0.4 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Centrifuge to remove cellular material. Transfer 0.5 mL CSF to an ARUP Standard Transport Tube.
Storage Instructions
Refrigerated
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 1 week |
| Frozen | 2 weeks |
Other tests from different labs that may be relevant