Beta-2 Microglobulin, CSF
Also known as: B2M CSF
Use
The Beta-2 Microglobulin, CSF test is used to evaluate involvement of the central nervous system in certain inflammatory or B-cell proliferative diseases. Elevated levels of Beta-2 Microglobulin in the cerebrospinal fluid (CSF) can indicate an active disease process affecting the central nervous system. This test is particularly useful in the assessment of diseases like multiple sclerosis and central nervous system involvement in systemic lupus erythematosus.
Special Instructions
The test is performed on cerebrospinal fluid (CSF) specimens. Proper specimen collection and preparation are crucial for the accuracy of test results. Centrifuge the CSF to remove cellular material before transferring it to an ARUP Standard Transport Tube.
Limitations
Beta-2 Microglobulin, CSF levels may be influenced by factors other than central nervous system diseases, such as systemic inflammation or renal impairment, which can result in elevated levels. These conditions may confound the interpretation of test results. Additionally, this test, developed and its performance determined by ARUP Laboratories, has not been cleared or approved by the US FDA, although it is performed in a CLIA-certified laboratory.
New York Approved
Methodology
Immunoassay (Quantitative Immunoturbidimetry)
Biomarkers
LOINC Codes
- 1951-3
Result Turnaround Time
0-1 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
0.5 mL
Minimum Volume
0.4 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Centrifuge to remove cellular material. Transfer 0.5 mL CSF to an ARUP Standard Transport Tube.
Storage Instructions
Refrigerated
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 1 week |
| Frozen | 2 weeks |