Cytokeratin 20 (CK 20) by Immunohistochemistry
Also known as: CYTO20 IHC
Use
This test provides technical immunohistochemical staining for Cytokeratin 20 (CK 20) on tissue specimens or cell blocks. CK 20 expression aids in identifying epithelial tumors in diagnostic pathology, particularly in distinguishing carcinomas of gastrointestinal origin and other tissues, although interpretation is not provided by ARUP (technical service only).
Special Instructions
Order via electronic request or use ARUP Immunohistochemistry Stain Form (#32978) if electronic ordering is unavailable. Submit tissue blocks or at least 5 unstained (3–5‑micron) positively charged slides (minimum 2 slides); do not oven bake precut slides. Use ARUP tissue transport kit #47808. Transport at room temperature or refrigerated; ship cooled in summer. This is a stain-and-return technical service only.
Limitations
This test does not include pathologist interpretation—interpretation must be done by the ordering provider. Unacceptable: non‑representative tissue, depleted specimens, frozen specimens. Slides must not be oven baked. Frozen specimens are unacceptable. Stability is indefinite at ambient or refrigerated conditions.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 94736-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Transport tissue block or 5 unstained (3‑ to 5‑micron thick) positively charged slides in a tissue transport kit (ARUP supply #47808).
Storage Instructions
Protect paraffin block and/or slides from excessive heat.
Causes for Rejection
Non‑representative tissue type; depleted specimens; precut slides oven baked; frozen specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |